A1c Discordance in Diabetes Patients

Endocrine Research Society25 enrolled

Overview

HbA1c is used as a gold standard to see whether patients have optimal glycemic control. Today, many physicians rely solely on HbA1c to change medication. However, there is a select group of patients that have low average glucose levels but high HbA1c levels. The investigators believe that these patients are fast glycators meaning that they incorporate sugar into their hemoglobin faster than normal. The investigators want to determine whether these patients are fast glycators.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

SCREENING

Masking

NONE

Enrollment

Conditions

Diabetes Mellitus

Interventions

Fast GlycatorOTHER

The subjects enrolled in this study will have a fructosamine test and blood drawn to see whether they are fast glycators

ControlOTHER

These patients will have their blood drawn to know what the normal glycation rate is in diabetic patients

Eligibility

Sex: ALLMin age: 25 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient with diabetes * Patients who test their sugar levels at least 3 times daily * Recorded diary of sugar levels for the past month * Willingness to have blood drawn * Willingness to allow their blood sugar diary to be photocopied * Estimated average glucose as derived from A1c is ≥ 4 mmol from measured glucose from self-monitoring blood glucose testing Exclusion Criteria: * Patient with medical conditions that may affect their study participation or results will be excluded. * Patients who are anemic * Renal insufficient with a serum creatinine level \> 200 μmol/L

Outcomes

Primary Outcomes

Primary endpoint is to see whether they are fast glycators

Time frame: One Week

Secondary Outcomes

A secondary endpoint includes adverse events such as unplanned hospitalizations for any cause that last more than 24 hours

Time frame: One Week

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.