Effects of Betaine Supplementation on Strength and Muscle Creatine Content

University of Sao Paulo40 enrolled

Overview

It has been suggested that betaine supplementation may improve muscle strength by increasing muscle creatine content. However, there is no data supporting this assumption. The investigators speculate that betaine supplementation could enhance intramuscular creatine content, which would result in strength improvements.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

DOUBLE

Enrollment

Conditions

Healthy Subjects

Interventions

creatineDIETARY_SUPPLEMENT

20g/d throughout 10 days

betaineDIETARY_SUPPLEMENT

2g/d throughout 10 days

dextroseDIETARY_SUPPLEMENT

dextrose (placebo), 20 g/d throughout 10 days

creatine plus betaine

Eligibility

Sex: MALEMin age: 18 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * physically inactive * non-obese Exclusion Criteria: * skeletal muscle disturbance * cardiovascular disturbance * use of dietary supplements

Locations (1)

University of Sao Paulo

São Paulo, São Paulo, Brazil

Outcomes

Primary Outcomes

strength

Time frame: after 10 days

Secondary Outcomes

intramuscular creatine content

Time frame: after 10 days

Data from ClinicalTrials.gov

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