The purpose of this study is to increase the knowledge of the possible diagnostic effect of exercise induced bronchoconstriction performing a repeated exercise challenge test.
Prior studies have shown that the intensity influences the sensitivity of exercise challenge tests (ECT) and that a heart rate-based protocol does not ensure sufficient exercise intensity to induce bronchoconstriction. It is not common clinical practice to perform a pre ECT to establish maximal heart rate or maximal oxygen uptake. The heart rate formula recommended by ATS (HRmax= 220-age) is usually applied to determine recommended intensity of the ECT. Conducting a second ECT, based on the knowledge of the first test, introduce the possibility to adjust the intensity on an individual basis. In addition, based on clinical experience, patients may seem reluctant to perform maximal the first time they undergo an ECT on a treadmill. The hypothesis is that patients are less reluctant to perform maximal the second time they undergo the test when they are more accustomed to the procedure and the treadmill by itself.
Study Type
OBSERVATIONAL
Enrollment
20
Klinikk for allergi og luftveissykdommer
Oslo, Ullevål, Norway
Forced expiratory volume in one second (FEV1)
Time frame: up to 4 weeks
Forced vital capacity (FVC)
Time frame: up to 4 weeks
Forced expiratory flow at 50 % FVC(FEF50%)
Time frame: up to 4 weeks
Fractional exhaled nitric oxide (FENO)
Time frame: up to 4 weeks
Total lung capacity (TLC)
Time frame: up to 4 weeks
Specific airway resistance (sRAW)
Time frame: up to 4 weeks
Specific airway conductance (sGAW)
Time frame: up to 4 weeks
Residual volume (RV)
Time frame: up to 4 weeks
Diffusing capacity (TLCO)
Time frame: up to 4 weeks
Maximum voluntary ventilation (MVV)
Time frame: up to 4 weeks
Breathing reserve (BR)
Time frame: up to 4 weeks
Respiratory exchange ration (RER)
Time frame: up to 4 weeks
Oxygen uptake peak (VO2 peak)
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Time frame: up to 4 weeks
Heart rate peak (HR peak)
Time frame: up to 4 weeks
Ventilation peak (VE peak)
Time frame: up to 4 weeks