Clinical Study to Determine if Ecopipam Can Reduce Urges to Gamble

Inclusion Criteria: * Subject must be diagnosed with Pathological Gambling according to DSMIV criteria * Subject must have at least 2 episodes of gambling behavior within the previous 2 weeks before screening * Subject must have gambling urges of at least moderate intensity Exclusion Criteria: * Subjects must not have unstable medical illness or clinically significant abnormalities on lab tests, ECG, or physical exam * Subjects with major depressive episode within the last 2 years * Subjects with a history of attempted suicide * Subjects with first degree relative with major depressive episode that resulted in hospitalization, attempted or completed suicide * Subjects with a history of epilepsy or seizures * Subjects with a myocardial infarction (heart attack) with in the last 6 months * Subjects with a lifetime history of bipolar disorder, dementia, schizophrenia, or any psychotic disorder * Subjects with current of recent DSM-IV diagnosis of substance abuse or dependence (with the exception of nicotine)