Acute Neurocardiogenic Injury After Subarachnoid Hemorrhage.

Direction Centrale du Service de Santé des Armées30 enrolled

Overview

The aim of this study is to describe acute neurocardiogenic injury after subarachnoid hemorrhage assessed with cardiac 123I-MIBG scintigraphy and 18F-FDG PET/CT during the first week and the first six months after SAH. The study hypothesis is that the evolution of the cardiac disturbances follows the clinical evolution.

The cardiac metabolic disturbance are assessed by a 18F-FDG PET/CT in the first week after SAH and monthly until normal result. The myocardial sympathetic innervation is assessed by a cardiac 123I-MIBG scintigraphy in the first week after SAH and six months later. Clinical outcome is assessed by Glasgow Outcome Scale, modified Rankin Scale and MOS-SF36 at 1, 3 and 6 months after SAH.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Subarachnoid Hemorrhage

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age * SAH * Hospitalization in the Military Teaching Hospital Sainte Anne Exclusion Criteria: * Refusal of consent

Locations (1)

Intensive Care Unit, Military Teaching Hospital sainte Anne

Toulon, France

Outcomes

Primary Outcomes

cardiac 18F-FDG PET

Time frame: first week after SAH

Secondary Outcomes

cardiac 123I-MIBG scintigraphy

Time frame: first week after SAH

cardiac 18F-FDG PET

Time frame: one month after first cardiac 18F-FDG PET

cardiac 123I-MIBG scintigraphy

Time frame: Six months after SAH

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.