Influence of Organic Anion Transporting Polypeptide1B1(OATP1B1) Genotype on Rosuvastatin PK, PD and Lipid Profiles

Inclusion Criteria: * Age: Between 20 to 50 years of age, inclusive (age based on the date to give the informed consent) * Weight: Over 55 kg, within ±20% of ideal body weight * Must be reliable and willing to make themselves available during the study period * Must be willing to give blood sample for genotyping Exclusion Criteria: * History of significant clinical illness needs medical caution, including cardiovascular, immunologic, hematologic, neuropsychiatric, respiratory, gastrointestinal, hepatic, or renal disease or other chronic disease * History of a significant surgical resection of gastrointestinal tract except appendectomy * History or evidence of drug abuse * Use any medication during the last 14 days period before first dosing * Hypersensitivity to HMG-CoA reductase inhibitor * Judged to be inappropriate for the study by the investigator