Development of Bone Grafts Using Adipose Derived Stem Cells and Different Scaffolds

University of Zurich33 enrolled

Overview

The repair of large osseous defects remains still unsolved. Aim of this study is to isolate and cultivate fat-derived progenitor cells and differentiation into osteoblasts. Therefore, our research idea is to pre-engineer large synthetic bone grafts and study the vascularization process in vivo.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Overweight

Interventions

Cell CulturePROCEDURE

Aim of this study is to isolate and cultivate fat-derived progenitor cells and differentiation into osteoblasts. Therefore, our research idea is to pre-engineer large synthetic bone grafts and study the vascularization process in vivo.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion criteria: * German-speaking patients aged 18-70 admitted to the Clinic of Reconstructive surgery for reconstructive surgery and fat-excision. Exclusion criteria: * Drug-abuse, neoplasia and metabolic disorders

Locations (1)

University Hospital Zurich, Clinic of Reconstructive Surgery

Zurich, Canton of Zurich, Switzerland

Data from ClinicalTrials.gov

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