The researchers will investigate whether exercise could provide positive effects on general brain functions in elderly people with impaired glucose tolerance.
The age-related degradation of cognitive functions even to the point of neurodegenerative disorders such as Alzheimer's disease are a growing public-health concern with devastating effects. Referring to animal data, empirical studies, and pilot human trials, exercise should improve cognitive functions such as learning and memory. To test this hypothesis, the researchers study general brain functions in elderly subjects (50-80 years old) with impaired glucose tolerance during a short term exercise program.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
46
6 months of aerobic exercise
Department of Neurology, Charité Universitätsmedizin
Berlin, State of Berlin, Germany
Auditory Verbal Learning Task
Time frame: Prior to intervention and after 6 months of intervention
Functional/Structural brain changes
Time frame: Prior to intervention and after 6 months of intervention
Plasma biomarkers
Time frame: Prior to intervention and after 6 months of intervention
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