Radiocontrast Media Induced Hyponatremia

N/AUnknownNCT01219270

Gachon University Gil Medical Center100 enrolled

Overview

Osmolality of contrast media can be resulted in translocational hyponatremia after percutaneous coronary intervention.

Radiocontrast media after percutaneous coronary interventioncan lead to increased osmolaliry of plasma, which results in translocational hyponatremia. The investigator will exam the incidence of hyponatremia after percutaneous coronary intervention, and will evaluate the underlying mechanism related to hyponatremia including translocational hyponatremia, or osmotic natriuresis.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Percutaneous Coronary Intervention

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who receive contrast media during percutaneous coronary intervention Exclusion Criteria: * Patients who have sensitivity to contrast media. * Liver cirrhosis * Hypothyroidism * SIADH * Patients who receive IVIG or mannitol.

Locations (1)

Gachon University Gil Hospital

Incheon, South Korea

RECRUITING

Outcomes

Primary Outcomes

Incidence of contrast media induced translocational hyponatremia

The will investigator evaluate how often translocational hyponatremia may develop after percutaneous coronary intervention.

Time frame: 01/10/2010-28/02/2011

Secondary Outcomes

Renal function is affected by the incidence of translocational hyponatremia.

Reduced renal function and urine output contribute the development of contrast media induced translocational hyponatremia.

Time frame: 01/10/2010-28/02/2011

Data from ClinicalTrials.gov

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