Single dose tranexamic acid (TA) before dacryocystorhinostomy (DCR) operation: a prospective, double blind, placebo controlled study. The study hypothesis: TA in DCR might reduce the intraoperative and postoperative bleeding in DCR surgery, and might reduce the duration of the surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
80
Single dose TA 500mg or placebo will be given in DCR surgery right after the first surgical incision.
5cc saline solution
Dept. of Ophthalmology, HaEmek medical center
Afula, Afula, Israel
Duration of DCR surgery in minutes and amount of blood loss in milliliters during surgery.
Time frame: Blood loss will be measured at the end of DCR operation from the suction bowel. Duration of surgery will be caculated by registering time of operation start and end.
Late onset postoperative epistaxis or periorbital hematoma
Time frame: 8 days
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