Effect of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Endothelial Function

Inclusion Criteria: 1. STEMI 2. no prior treatment with statins Exclusion Criteria: 1. age below 18 or above 81 years 2. unconscious patients 3. serum creatinine \> 176μmol/L 4. total-cholesterol \> 7.0 mmol/l 5. hypothyreoidism ((TSH \> 1.5 x ULN (upper limit of normal)) 6. current liver disease (ALAT \> 2 x ULN) 7. unexplained creatine kinase \> 3 x ULN 8. alcohol or drug abuse within the last five years 9. prior myopathy or serious hypersensitivity reaction caused by statins 10. women with childbearing potential who were not using chemical or mechanical contraception 11. pregnant or breastfeeding women 12. history of malignancy unless a disease-free period of more than five years was present 13. patients with abnormal lung function test (LFT) 14. participation in another investigational drug study less than four weeks before enrolment in the present study 15. treatment with cyclosporine or fibrates.