Dehydrated fruit and vegetable concentrates provide an accessible form of phytonutrient supplementation that may offer cardioprotective effects. This study assessed the effects of encapsulated fruit and vegetable juice powder concentrates on endothelial function and cardiac risk markers in subjects in a randomized, double blind, placebo controlled crossover clinical trial with three treatment arms.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
64
Blend 1 consists of a combination of Juice Plus+® Orchard (Fruit), Garden (Vegetable), and Vineyard (Berry) blends
Blend 2 consists of a combination of Juice Plus+® Orchard (Fruit) and Garden (Vegetable) blends
Placebo capsules are provided by the study sponsor and are identical in appearance to active treatments to ensure blinding.
Griffin Hospital
Derby, Connecticut, United States
Endothelial Function
Endothelial function as flow-mediated dilatation (FMD)
Time frame: 8-weeks
Weight
Measured on a calibrated scale
Time frame: 8-weeks
Lipid panel
Total cholesterol, TG, HDL, LDL, ratio
Time frame: 8-weeks
Insulin
Serum insulin
Time frame: 8-weeks
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