A Study of Linifanib (ABT-869) in Combination With Carboplatin/Paclitaxel in Japanese Subjects With Non-Small Cell Lung Cancer (NSCLC)

Inclusion Criteria * The subject must be 20 and older years of age. * The subject must have cytologically or histologically confirmed non-squamous NSCLC. Subjects may have a mixed histology but must be predominantly non-squamous to be eligible. * The subject must have advanced or metastatic (Stage IV \[According to American Joint Committee on Cancer (AJCC) staging manual, 7th edition\]) disease that is not amenable to surgical resection or radiation with curative intent. * The subject must have not received prior chemotherapy for NSCLC. * The subject has measurable disease, defined as at least 1 unidimensionally measurable lesion on a CT scan as defined by Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1. * The subject has an Easter Cooperative Oncology Group (ECOG) Performance Score of 0-1. * The subject must have adequate bone marrow, renal and hepatic function. Exclusion Criteria * The subject has hypersensitivity to paclitaxel or to other drugs formulated with polyethoxylated castor oil (Cremophor). * The subject has received any anti-cancer therapy for treatment of NSCLC including investigational agents, immunotherapy, traditional Chinese medicine/herbal remedies, hormonal, "targeted" agents (i.e., erlotinib, imatinib), biologic therapy or cytotoxic chemotherapy (i.e., alkylating agents, microtubule inhibitors, antimetabolites). * The subject has a history of another active cancer within the past 5 years except cervical cancer in situ, in situ carcinoma of the bladder, squamous cell or basal cell carcinoma of the skin. * The subject has active ulcerative colitis, Crohn's disease, celiac disease or any other conditions that interfere with absorption. * The subject has a medical condition, which in the opinion of the study investigator places them at an unacceptably high risk for toxicities. * The subject is pregnant or breast feeding. * The subject has NSCLC with a predominant squamous cell histology.