Fibroid Ablation Study

Inclusion Criteria: * 28 years of age or older * Regular, consistent menstrual cycles * History of excessive bleeding * One Menstrual Pictogram score ≥ 120 during a one-month screening period * Baseline Uterine Fibroid Symptom \& Quality of Life (UFS-QOL) Symptom Severity Subscale (SSS) score ≥ 20 * Between 1 and 5 Target Fibroids between 1 cm and 5 cm and/or maximum volume 82.4cc * At least one fibroid must indent the endometrium * Subject is not at material risk for pregnancy. * Subject is willing to maintain use or non-use of hormonal contraception * Subject is willing to have uniform maintenance (use or non-use) of any antifibrinolytic or nonsteroidal anti-inflammatory agents Exclusion Criteria: * Subserosal fibroids with bulk symptoms * Presence of type 0 intracavitary fibroids * Any Target Fibroid \> 5 cm in maximum diameter with a volume \> 82.4cc * Any fibroid that obstructs access of the VizAblate probe * Postmenopausal by history * Desire for current or future fertility * Hemoglobin \< 6 g/dl * Pregnancy * Evidence of disorders of hemostasis * Use of Gonadotropin-releasing hormone (GnRH) agonist or implantable or injectable progestin and/or estrogen, Selective Estrogen Receptor Modulators (SERM) or selective progesterone receptor modulator (SPRM) * Short-term use of hormonal medication for management of bleeding * Evidence for current cervical dysplasia * Endometrial hyperplasia * Confirmed abdominal / pelvic malignancy within the previous five years * Active pelvic infection * Clinically significant adenomyosis * Previous uterine artery embolization. Previous surgical or ablative treatment for fibroids or menorrhagia within previous 12 months * Current use of anticoagulant therapy * Need for emergency surgery to treat fibroid symptoms * Concomitant intrauterine polyps \> 1.0 cm * Contraindication to MRI * Renal insufficiency * Uncontrolled hypertension lasting 2 years or more * One or more treatable fibroids that are calcified * Chronic pelvic pain * Presence of an extrauterine pelvic mass * Presence of a tubal implant for sterilization * Previous pelvic irradiation * Endometrial cavity length \< 4.5 cm