NGAL Predictive Value of Acute Kidney Failure After Cardiac Surgery in Patients With Preoperative Chronic Kidney Failure

Hopital Jean Minjoz100 enrolled

Overview

Primary endpoint: To evaluate predictive value of plasmatic levels of Neutrophil Gelatinase Associated Lipocalin (NGAL) to reveal acute kidney failure after cardiac surgery in patients with preoperative chronic kidney failure Secondary endpoint is to obtain threshold values of NGAL.

(N/A)

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Preoperative KIDNEY FAILURE, CHRONIC Postoperative KIDNEY FAILURE, ACUTE Cardiac Surgical Procedures

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Renal clearance less than 60 mL/min * Able to give written consent * Elective valve surgery * Elective CABG surgery Exclusion Criteria: * Less than 18 years old * Iodine injection within 3 days before surgery * Iodine injection within 24 first postoperative hours * preoperative infection * evolutive cancer disease * Refusal * Pregnancy * Unable to give written consent

Locations (1)

Centre hospitalier Universitaire (CHU) Jean Minjoz

Besançon, Franche-Comté, France

RECRUITING

Outcomes

Primary Outcomes

Neutrophil Gelatinase Associated Lipocalin (NGAL) level

Time frame: From surgery to discharge from hospital

Data from ClinicalTrials.gov

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