Tear Osmolarity Over Time With Artificial Tears

Hom, Milton M., OD, FAAO48 enrolled

Overview

The effect of artificial tears on tear osmolarity

Tear osmolarity measures the amount of solutes in the human tear film. The higher the reading, the more likely the patient has dry eyes. Some say it has "potential to be the gold standard" of dry eye testing. The investigators study the tear osmolarity at different time points after instillation of artificial tears.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

DOUBLE

Enrollment

Conditions

Dry Eye

Interventions

Artificial tearsDRUG

Instill one drop of artificial tears

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Between the ages of 18 and over inclusive. Males or females Any race or ethnic background Patient is in generally good \& stable overall health. Patient likely to comply with study guidelines \& study visits. Informed consent signed. Subjective evaluation of symptom of dryness (SESoD): Score 2 (Mild) \- Exclusion Criteria: Corneal refractive surgery within 6 months of this study. Intra-ocular surgery within 6 months or ocular laser surgery within 6 months. Pregnant or lactating women. Ocular pathology (includes glaucoma and cataract), which could impact results and/or place patient at risk. Corneal staining Grade 3 or higher No Restasis for past 3 months Discontinue topical medications for at least 1 week

Locations (1)

Milton M. Hom, OD, FAAO.

Azusa, California, United States

Outcomes

Primary Outcomes

Tear osmolarity

Tear osmolarity measured with TearLab instrument

Time frame: 2 days

Data from ClinicalTrials.gov

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