Study for Effectiveness Evaluation of Panax Ginseng, Vitamins and Minerals (Natugerin®) in Improvement of Stress and Fatigue

Inclusion Criteria: * Agree with all study procedures, signing the IC in two ways, by his own free will; * Patients older than 18 years, male or female, regardless of ethnicity or social class; * Presence of pictures of mild to moderate stress, confirmed with the aid of the Stress Symptom Inventory (ISS), which considers stress and mild to moderate classification Alert classification Resistance; * Presence frame of fatigue with a score greater than 36 according to the Fatigue Severity Scale (FSS). Exclusion Criteria: * Participation in clinical trials in the 12 months preceding the survey; * Current treatment with drugs that are stimulants or central nervous system depressants such as hypnotics, anxiolytics, antipsychotics, antidepressants, statins and muscle relaxants; * Alternative Therapies that scientifically, or have no influence in the tables of stress or fatigue as acupuncture or relaxing massages; * Treatment psychotherapeutic medication or not; * Current treatment or prediction of treatment with oral anticoagulants (due to interaction with the tocopherol); * Women who are pregnant or lactating; * Patients with lactose intolerance; * Patients allergic to soy or peanuts; * chronic renal failure; * Patients using other multivitamins or individual vitamins such as vitamin D and / or A. * Chronic alcoholism; * Patients with clinical diagnosis of diseases causing severe chronic pain or adversely affect the clinical interpretation as fibromyalgia, multiple sclerosis, neuropathies and myopathies; * Patients with hypothyroidism or hyperthyreosis diagnosed clinically; * Patient history and physical examination suggestive of severe hepatorenal failure; * Patients with decompensated diabetes mellitus (fasting glucose above 180 mg / dL); * Patients being treated for cancer; * Amendment of the routine of life during the study as early vacation or suspected change in working hours; * Patients with complaints of excessive sleepiness caused by organic source frameworks such as sleep apnea and morbid obesity (BMI above 35); * History of hypersensitivity to any component of the product under investigation; * Any finding of clinical observation (clinical history or physical examination) that is interpreted by the physician investigator as a risk to the patient's participation in the study.