Clinical Trial Comparing Continuous Versus Intermittent Hemodialysis in ICU Patients

Charite University, Berlin, Germany252 enrolled

Overview

The mortality of acute renal failure (ARF) remains to be high (around 60-70%) despite manifold improvements in ICU care. At present, it is not clear if the method chosen for renal replacement therapy, i.e. intermittent haemodialysis (IHD) or continuous haemofiltration (CVVH), might impact on the outcome of these patients. For this purpose, a prospective randomised clinical study of the effect of continuous versus intermittent renal replacement therapy on the mortality and outcome of acute renal failure will be performed.

please see above

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

252

Conditions

Acute Renal Failure

Interventions

RRT for acute kidney failure using the CVVH methodOTHER

patients randomized to receive CVVH

RRT for acute kidney failure using the IHD (intermittent HD)OTHER

patients randomized to receive IHD

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * all ICU patients requiring renal replacement therapy Exclusion Criteria: * patient denies informed consent * patient not requiring intensive care therapy * kidney transplanted patients * chronic renal failure (serum creatinine \> 3mg/dl)

Locations (1)

Charite University Medicine

Berlin, State of Berlin, Germany

Outcomes

Primary Outcomes

Survival at 2 weeks after RRT

Time frame: 2 weeks after RRT in follow-up

Data from ClinicalTrials.gov

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