The purpose of this study is to examine the effect of two different physical exercise protocols on changes in coronary artery plaque composition and development of in-stent restenosis in patients treated with percutaneous coronary intervention with stent implantation. The investigators will compare aerobic interval training and moderate continuous training. Both exercise protocols have a duration of 12 weeks. The investigators hypothesize that aerobic interval training is superior to moderate continuous training regarding effects on the composition of coronary artery plaques and a reduction in the development of in-stent restenosis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
Three training sessions per week in a total of 12 weeks
Three training sessions per week in a total of 12 weeks
Department of Cardiology
Trondheim, Norway
Artery plaque composition evaluated by intravascular ultrasound and virtual histology
Findings at 12 weeks will be compared to baseline results
Time frame: After 12 weeks
Occurrence of in-stent restenosis related to endothelial dysfunction, inflammatory biomarkers and the dimension of the main left coronary artery
Findings at 12 weeks will be compared to baseline results
Time frame: After 12 weeks
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