Prospective Study of the Impact of Systemic Corticosteroid Use on Measures of Sleep Disordered Breathing

Rambam Health Care Campus20 enrolled

Overview

Weight gain is both a significant risk factor for obstructive sleep apnea and a side-effect of long-term systemic steroids therapy. This study aimed to investigate the impact of long-term systemic steroid treatment on sleep apnea.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sleep Apnea

Interventions

sleep studyOTHER

The polysomnography (PSG) (Alice 3 System; Healthdyne, Atlanta, GA) consisted of continuous polygraphic recording from surface leads for electroencephalography, electrooculography, electromyography, electrocardiography, thermistors for nasal and oral airflow, thoracic and abdominal impedance belts for respiratory effort, pulse oximeter for oxyhemoglobin level, tracheal microphone for snoring, and sensors for leg and sleep position

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * For inclusion, a scheduled therapy with a minimum daily dose of 10 mg prednisone (or equivalent) for at least 3 months was required Exclusion Criteria: * Patients younger than 18 years and those with known sleep apnea or other forms of sleep-disordered breathing were excluded

Locations (1)

Rambam health care campus

Haifa, Israel

Outcomes

Primary Outcomes

apnea-hypopnea index

Time frame: 3 months

Secondary Outcomes

sleep study variables

apnea-hypopnea interval desaturation at the end of apnea interval snoring intensity

Time frame: 3 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.