Safe Use of Heparin Sodium in Patients With Chronic Renal Failure.

Inclusion Criteria: * Adults of both sexes, regardless of color or social class; * Age above 18 years; * Patients who agree to participate in the study and signed the free and informed consent (attached); * Insufficient patients in chronic renal dialysis scheme (3 times per week); * Low Chronic Renal indication of anticoagulant during dialysis. Exclusion Criteria: * Not agree to the terms described in informed consent; * Patients with sensitivity to heparin sodium; * Volunteer search with hypersensitivity to benzyl alcohol; * Patients with a history of bleeding or change in blood clotting that can aggravate or terminate the clinical picture, such as tables of gastric ulcer; * Patients with a history of peptic ulcer; * Patients with cancer of any etiology, because of the possibility of compromising the function of the variable coagulation; * Patients in a period of pregnancy and postpartum; * Individuals with genetic abnormality of clotting system; * Patients polytraumatized; * Patients in use of glucocorticoids for at least 1 month; * Patients in use of other anticoagulants; * Patients with high rate of bleeding; * Patients undergo any surgery performed less than 15 days because of the risk of the formation of hematomas at the site of surgery; * Patients in use of drugs that affect the hemostasis; * In addition to these, clinical characteristics that the medical criteria, can interfere with the study.