This study is to evaluate pharmacokinetic-pharmacodynamic property of C3G after administration of Mulberry fruit extract to 12 healthy Korean volunteers. Plasma concentration of C3G and the antioxidative markers such as total antioxidative capacity and attack of free oxygen radical will be measured. Additional objective is to investigate the multiple dose (2 weeks) safety of daily 1000mg Mulberry fruit extract. This study, as an exploratory trial, does not required statistical hypothesis.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Masking
NONE
Enrollment
12
1000 mg oral daily dose for 2 weeks
Seoul St.Mary's Hospital
Seoul, South Korea
Cmax - Maximum Observed Concentration - C3G in Plasma
Time frame: Blood samples collected over 6 hours
AUC0-inf - Area Under the Concentration-time Curve From Time Zero to Infinity (Extrapolated) - C3G in Plasma
Time frame: Blood samples collected over 6 hours
Antioxidative markers
Time frame: 2 weeks
Number of Participants with Adverse Events
Time frame: for 4 weeks
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