An eyelid stye, or chalazion, is the most common eyelid ailment, and is caused by the blockage of one of the oil secreting glands of the eyelid (meibomian glands). This leads to a typically painful, swollen, and red eyelid bump that lasts from days to weeks and months. The chalazion may cause tearing, pressure on the cornea, and irritation, all of which contribute to its morbidity. There are many anecdotal first line treatments for this condition, including warm compresses to the eyelid, topical antibiotics, topical steroids, topical combination antibiotic/steroid, and oral antibiotics. There have been no clinical trials to compare the efficacy of any of these conservative treatments. We wish to determine the most effective conservative medical treatment for chalazia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
150
In addition to hot compress, Tobramycin drops will be given to the affected eye 3x/day, and Tobramycin ointment will be given at night before bed.
In addition to hot compress, Tobramycin/Dexamethasone drops will be given to the affected eye 3x/day, and Tobramycin/Dexamethasone ointment will be given at night before bed.
Hot compresses 3x/day to eyelids
Elmhurst Hospital Center
Elmhurst, New York, United States
Icahn School of Medicine at Mount Sinai
New York, New York, United States
St. Joseph's Hospital Eye Clinic
Stoney Creek, Ontario, Canada
Number of Participants With Complete Resolution
Defined as number of patients with chalazion size regression of 100%
Time frame: 4-6 weeks
Chalazion Size Difference Post-Treatment
Change of size of eyelid chalazion in millimeters from baseline to 4-6 weeks post-treatment
Time frame: baseline and 4-6 weeks
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