The Role of Corticosteroids and Vestibular Exercises in Recovery of Vestibular Neuritis

Early Phase 1UnknownNCT01231009

Aristotle University Of Thessaloniki40 enrolled

Overview

Aim of present study is to determine whether corticosteroids and vestibular exercises are equal effective in the recovery of balance in patients with acute vestibular neuritis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Vestibular Neuritis

Interventions

CorticosteroidsDRUG

Intravenous Dexamethasone, 8mg three times per day tapering down for 7 days Per os dexamethasone, 2mg per day tapering down for 7 days

Vestibular exercisesOTHER

Vestibular exercises in order to enhance vestibulo-ocular reflex for 15 days under the suspicion of physiotherapist

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with history of acute or sub-acute rotatory vertigo with postural imbalance, nausea and imbalance. * Horizontal-rotatory spontaneous nystagmus. Exclusion Criteria: * History of vestibular disfunction before the acute onset of symptoms * Simultaneous Hearing loss * Neurologic disorder * Pregnancy or lactation * History of psychiatric disorders * History of glaucoma * Diabetes * Hypertension * Contraindication in receiving corticosteroids

Locations (1)

1st ENT Department, AHEPA University Hospital

Thessaloniki, Greece

RECRUITING

Outcomes

Primary Outcomes

clinical recovery of vestibular function

clinical examination (nystagmus, Romberg test, head-thrust test, head-shaking test) and questionnaires (Greek edition of Dizziness Handicap Inventory and European Evaluation of Vertigo Scale)

Time frame: 1 year

Laboratory recovery of vestibular

caloric test and vestibular evoked myogenic potentials

Time frame: 1 year

Central Contacts

John Goudakos, MD, MSc

CONTACT

00306944183682 jgoudakos@gmail.com

Data from ClinicalTrials.gov

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