The Optimal Effect Site Concentration of Propofol for Conscious Sedation in Elderly Male Patients Undergoing Urologic Surgery Under Spinal Anesthesia With or Without Intrathecal Fentanyl

Yonsei University43 enrolled

Overview

Since intrathecal fentanyl is known to sedation effect, intrathecal fentanyl will result in lowering propofol requirement for conscious sedation under spinal anesthesia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

TRIPLE

Enrollment

Conditions

Conscious Sedation Under Spinal Anesthesia

Interventions

propofolDRUG

1.1 mcg/ml for initial effect site concentration during spinal anesthesia (The effect site concentration will be changed at each subject by Dixon's up-and-down method.)

Eligibility

Sex: MALEMin age: 60 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * elderly male patients undergoing urologic surgery under spinal anesthesia Exclusion Criteria: * patients with any co-morbidity

Locations (1)

Severance Hospital

Seoul, South Korea

Outcomes

Primary Outcomes

Cerebral state index

every 1 minute(up to 10-minute) after getting effect site concentration of propofol

Time frame: 1 minute

Data from ClinicalTrials.gov

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