Impact of Sperm DNA Integrity on In Vitro Cycles

Northwell Health420 enrolled

Overview

Sperm DNA integrity will be measured via the Toluidine Blue Assay (TBA) for patients undergoing In Vitro Fertilization (IVF); the study will determine correlations, if any, between IVF success and sperm DNA integrity.

Study Type

OBSERVATIONAL

Enrollment

420

Conditions

Male Infertility Unexplained Infertility Abortion, Habitual

Eligibility

Sex: MALE

Medical Language ↔ Plain English

Inclusion Criteria: * couple undergoing IVF at the Center for Human Reproduction * sperm sample given from partner (not a donor) Exclusion Criteria: * low sperm concentration (\<5 million/cc) * using a donor sample

Locations (1)

Center for Human Reproduction

Manhasset, New York, United States

Outcomes

Primary Outcomes

Pregnancy

detemining whether the sperm sample (tested for DNA integrity) used to insemenate IVF retrieved eggs, results in a live birth

Time frame: 9 months

Data from ClinicalTrials.gov

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