Tissue Composition of Newborn Infants of Obese and Lean Mothers

Hvidovre University Hospital270 enrolled

Overview

0-hypothesis: the tissue composition of newborn infants is not modified by lifestyle intervention during pregnancy

Obese pregnant women (BMI \> 30) are randomized to exercise, diet or control (1:1:1) in order to reduce weight gain during pregnancy. Shortly after birth, tissue composition will be measured (DEXA)in 200 infants (65 from each group). The amount of fat tissue is subsequently analyzed between the groups and compared to results from another 65 infants of lean mothers

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

270

Conditions

Obesity

Interventions

dietBEHAVIORAL

calorie restriction to reduce weight gain

ExerciseBEHAVIORAL

Exercise to reduce weight gain

Eligibility

Sex: ALLMax age: 3 DaysHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Healthy term neonates Informed and written consent from both parents - Exclusion Criteria: Sick or preterm infants No consent \-

Locations (1)

Hvidovre University Hospital

Hvidovre, Denmark

Outcomes

Primary Outcomes

amount of fat tissue

Time frame: at birth

Secondary Outcomes

birth weight

Time frame: at birth

Data from ClinicalTrials.gov

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