The purpose of this study is to describe long term (\> 96 weeks) efficacy and safety of Atazanavir-based regimens in real life setting.
Time perspective: Collection of historical data and longitudinal follow up. Patients will be enrolled in 2011/2012 but data will be collected from medical charts from ATV initiation date (Feb 2008 - July 2010) until July 2013 at the latest (if no ATV discontinuation, or death, or lost to follow up). Non probability sample: * Specialized HIV management centers will be contacted in order to recruit about 15-20 sites per country. * Each site will have to enroll an average of 8-12 consecutive patients (min:5; max:30) fulfilling the inclusion/exclusion criteria.
Study Type
OBSERVATIONAL
Enrollment
525
Proportion of patients remaining on ATV-based treatment over time
Every 6 months from ATV initiation till July 2013 at the latest (maximum follow-up time up to 5.5 years)
Time frame: Up to 5.5 years
Time to discontinuation of ATV
Time frame: Every 6 months up to 5.5 years
Reasons for ATV discontinuation
Time frame: Every 6 months up to 5.5 years
Percent of patients with HIV-1 ribonucleic acid (RNA) < 50 and < 500 c/mL
Time frame: Every 6 months up to 5.5 years
Mean change in HIV-1 RNA
Time frame: Every 6 months up to 5.5 years
Time to viral failure (HIV-1 RNA ≥ 50 and ≥ 500 c/mL)
Time frame: Every 6 months up to 5.5 years
Mean change in Cluster of differentiation 4 (CD4) cell count
Time frame: Every 6 months up to 5.5 years
Adverse events (AEs) related to ATV
Time frame: Every 6 months up to 5.5 years
Lipid profile
Time frame: Every 6 months up to 5.5 years
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