This clinical trial studies computer-guided glucose management systems in treating patients with hyperglycemia who have undergone blood and bone marrow transplant. A computer-guided glucose management system may help manage glucose levels in patients who have undergone blood or bone marrow transplant.
PRIMARY OBJECTIVES: I. To examine the ability of computer-guided glucose management system (CGGMS) algorithms to control glucose within or close to current University of Washington Medical Center (UWMC) intensive care unit (ICU) targets (100 to 140 mg/dl) in non-critically ill bone marrow transplant (BMT) adult (age \>= 18 years) patients. OUTLINE: Patients receive blood glucose management with intravenous (IV) insulin using Glucommander.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
19
Undergo blood glucose management using Glucommander
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, United States
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
Seattle, Washington, United States
Percentage of glucose values within target range (100-140) by using CGGMS
Standard statistical methods for rate and proportions will be used to assess binary outcomes, and standard methods for continuous data will be used for quantitative outcomes.
Time frame: Up to 2 years
Percentage of patients who experience hypoglycemia (defined as at least one blood glucose value less than 70)
Standard statistical methods for rate and proportions will be used to assess binary outcomes, and standard methods for continuous data will be used for quantitative outcomes.
Time frame: Up to 2 years
Percentage of patients who experience severe hypoglycemia (defined as at least one blood glucose value less than 40)
Standard statistical methods for rate and proportions will be used to assess binary outcomes, and standard methods for continuous data will be used for quantitative outcomes.
Time frame: Up to 2 years
Mean time to target range (100-140)
Standard statistical methods for rate and proportions will be used to assess binary outcomes, and standard methods for continuous data will be used for quantitative outcomes.
Time frame: Up to 2 years
Percentage of patients who experience hyperglycemia (defined as at least one blood glucose value greater than 200) 24 hours after initiation of infusion
Standard statistical methods for rate and proportions will be used to assess binary outcomes, and standard methods for continuous data will be used for quantitative outcomes.
Time frame: 24 hours after initiation of infusion
Percentage of patients who experience severe hyperglycemia (defined as at least one blood glucose value greater than 300) 24 hours after initiation of infusion
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Standard statistical methods for rate and proportions will be used to assess binary outcomes, and standard methods for continuous data will be used for quantitative outcomes.
Time frame: 24 hours after initiation of infusion
Number of values greater than 200 or less than 70 per patient per day of treatment
Standard statistical methods for rate and proportions will be used to assess binary outcomes, and standard methods for continuous data will be used for quantitative outcomes.
Time frame: Up to 2 years
Glucose variability (defined as standard deviation of individual blood glucose values)
Standard statistical methods for rate and proportions will be used to assess binary outcomes, and standard methods for continuous data will be used for quantitative outcomes.
Time frame: Up to 2 years
Nursing satisfaction evaluated by the Glucose Monitoring Tool Trial Evaluation Form
Standard statistical methods for rate and proportions will be used to assess binary outcomes, and standard methods for continuous data will be used for quantitative outcomes.
Time frame: Up to 2 years