Prognostic Impact of Anatomical Resection Vs. Non-anatomical Resection for HCC

University of Milan120 enrolled

Overview

Prognostic impact of AR vs NAR

Whether anatomical is better than non anatomical resection for HCC is still debated. This prospective randomized study aimed to address which approach is better in terms of patients prognosis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

120

Conditions

Patients Affected by Hepatocellular Carcinoma Disease-Free Survival Overall Survival

Interventions

anatomical liver resectionPROCEDURE

anatomical liver resection by means of IOUS-finger compression

Non-anatomical liver resectionPROCEDURE

non-anatomical liver resection

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * patient affected by single HCC * patients in whom liver resection is indicated * HCC without vascular invasion and/or thrombosis Exclusion Criteria: * multinodular HCC * metastatic disease * spontaneous tumor rupture

Locations (1)

IRCCS Istituto Clinico Humanitas

Rozzano, Milan, Italy

Outcomes

Primary Outcomes

the prognostic impact of anatomical resection by means of intraoperative ultrasound (IOUS) guided vessel compression versus nonanatomical resection in terms of disease free and overall survival

Time frame: 5-years

Secondary Outcomes

the impact of anatomical resection versus non-anatomical resection in terms of postoperative mortality and morbility

Time frame: 30 and 90 days

Central Contacts

Guido Torzilli, MD, PhD

CONTACT

+39 02 8224 guido.torzilli@unimi.it

Data from ClinicalTrials.gov

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