Background: Persistent severe pulmonary hypertension (PH) after mechanical valve replacement is a frequent finding in patients with severe valve-diseases. The reasons to develop PH are multifactorial and the prevalence of severe PH significantly worsens the patients´ outcome. Aims: (i) To define the prevalence of PH in patients after valve replacement and (ii) to identify factors predicting persistent PH. Methods: All patients which underwent valve replacement at our institution between the years 2008 -2010 will be screened retrospectively. Those patients with pre- procedural proven PH by means of right-heart catheterization will receive prospective follow-up with echocardiography. Diagnosis of persistent PH will be confirmed with right heart catheterization.
Study Type
OBSERVATIONAL
Enrollment
300
Medizinische Klinik II, University of Bonn
Bonn, Germany
Persistence of pulmonary hypertension after valve replacement for treatment of severe valve disease
Time frame: > 6 months after valve therapy
MACCE, all cause mortality during FU
Time frame: Within 24 months after valve therapy
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