The purpose of this study is to evaluate the efficacy of hypertonic saline vs. normal saline in the treatment of infants hospitalized for bronchiolitis, regarding length of hospital stay, oxygen requirements and clinical outcome.
Despite bronchiolitis is a very frequent disease among infants, there are still controversies regarding its treatment. Hypertonic saline has been proposed as useful treatment in these children, bur information is still controversial. The aim is to asses that using Nebulized Hypertonic Saline with bronchodilators (albuterol) may reduce the days of hospitalization and improve clinical outcomes in patients with acute bronchiolitis, compared with using Normal Saline with albuterol.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
82
3 cc nebulized hypertonic saline + albuterol 0.25 mg/kg/day, four times a day (QID), 5 days
3 cc nebulized normal saline + albuterol 0.25 mg/kg/day, four times a day (QID), 5 days
Hospital General de Niños Pedro de Elizalde
Buenos Aires, Buenos Aires F.D., Argentina
Hospitalization Days
hospitalization days
Time frame: Participants will be followed for the duration of hospitalization, an expected average of 4 days
Length of Oxygen Use
Length of oxygen use (days)
Time frame: Participants will be followed for the duration of hospitalization, an expected average of 4 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.