Reduction of Asthma Exacerbation Rate in Children by Non-invasive Monitoring of Inflammatory Markers in Exhaled Breath (Condensate): the RASTER Study

Inclusion Criteria: 1. already known with a diagnosis of asthma during at least 6 months 2. age between 6 and 17 years 3. reversibility to a bronchodilator (increase in FEV1 \> 9% of predicted value and/or 4. bronchial hyperresponsiveness to histamine \< 8 mg/ml. Exclusion Criteria: 1. cardiac abnormalities 2. mental retardation, congenital abnormalities or existence of a syndrome 3. active smoking 4. no technical satisfactory performance of measurements 5. no phone line or internet assess available at home.