The objective of this study is to evaluate the effect of mindfulness-based cognitive therapy (MBCT) on physical symptoms attributed to chemical exposures, psychological distress, illness worry, quality of life, and illness perceptions in patients suffering from multiple chemical sensitivity (MCS). Furthermore, a secondary objective is to evaluate whether a possible symptom reduction is mediated by an increased level of mindfulness. The primary hypothesis is that the self-reported severity of MCS symptoms and the degree to which chemical exposures causes symptoms and the impact on daily life will be significantly improved in the MBCT treatment group as compared to the control group.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
82
MBCT is partly based on the mindfulness-based stress reduction program (MBSR), developed by Jon Kabat-Zinn and colleagues, and partly on cognitive therapy for depression, the latter influence particularly expressed through the aspect of "decentering", meaning not accepting the content of thoughts as facts and not identifying with the thought. The MBCT programme in this study includes 2½ hours of training once a week for 9 weeks. In addition, participants are encouraged to practice at home for up to 45 min per day, 6 days a week during the entire course.
The Danish Research Centre for Chemical Sensitivities
Ledreborg Allé 40, 2., Gentofte, Denmark
The Quick Environmental Exposure and Sensitivity Inventory (QEESI)
QEESI is a screening instrument for MCS.
Time frame: 8 weeks, 1 year follow up
The brief illness perception questionnaire (Brief IPQ)
Time frame: 8 weeks, 1 year follow up
The Five Facet Mindfulness Questionnaire (FFMQ)
Time frame: 8 weeks, 1 year follow up
Symptom Check List 92 (SCL-92)
Time frame: 8 weeks, 1 year follow up
The Perceived Stress Scale (PSS-10)
Time frame: 8 weeks, 1 year follow up
The World Health Organization Quality of Life (WHOQOL-BREF)
Time frame: 8 weeks, 1 year follow-up
Rumination-reflection questionnaire (RRQ)
Time frame: 8 weeks, 1 year follow-up
Self compassion scale short form
Time frame: 8 weeks, 1 year follow up
The role work functioning index
Time frame: 8 weeks, 1 year follow-up
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