The purpose of this clinical research study is to investigate the efficacy of predosing patients undergoing cataract surgery with the potent corticosteroid difluprednate ophthalmic emulsion 0.05% compared to prednisolone acetate 1% on corneal edema (swelling), and retinal thickness.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
52
Difluprednate ophthalmic emulsion 0.05%: 29 days total, total of 7 drops prior to surgery, and 3 more following surgery while at the surgery center, then Q2H on day of surgery, then QID for 1 week, then BID for 1 week, then stop.
Prednisolone acetate 1% : 29 days total, total of 7 drops prior to surgery, and 3 more following surgery while at the surgery center, then Q2H on day of surgery, then QID for 1 week, then BID for 1 week, then stop.
Cincinnati Eye Institute
Edgewood, Kentucky, United States
Ophthalmic Consultants of Long Island
Lynbrook, New York, United States
Carolina Eyecare
Mt. Pleasant, South Carolina, United States
Assess change from Baseline on visual acuity, corneal edema, and retinal thickness at Day 1
Time frame: Change from Baseline in visual acuity, corneal edema, and retinal thickness at Day 1
Assess change from Baseline on visual acuity, corneal edema, and retinal thickness at Day 15
Time frame: change from Baseline on visual acuity, corneal edema, and retinal thickness at Day 15
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.