The aim of the investigators project is to explore the mechanisms of pain insensitivity in patients with schizophrenia, in order to prevent its invalidating consequences. The investigators will couple methods of experimental psychology with EEG and blood samplings, in order to distinguish the role of non-painful perception, attention, aversive effects, and pain expression, and the investigators will explore an original neurobiological hypothesis regarding the activation of opioid receptors.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
83
Service de Psychiatrie Adulte2, Place Saint-Jacques - ZA 481, Centre Hospitalier Saint-Jacques
Besançon, France
Service de Psychiatrie Adulte, Secteur G11, Centre Hospitalier de Erstein, 13 route de Krafft
Erstein, France
Centre d'évaluation et de traitement de la douleur, Hôpitaux Universitaires de Strasbourg
Strasbourg, France
Centre d'Investigation Clinique - Hôpitaux Universitares de Strasbourg
Strasbourg, France
Unpleasant stimuli
acute electrical stimulation
Time frame: during experimental session
Unpleasant stimuli
emotional pictures
Time frame: during experimental session
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Service de Psychiatrie - Hôpitaux Universitaires de Strasbourg
Strasbourg, France