The Effect of Selective Laser Trabeculoplasty (SLT) on Ocular Rigidity

Technische Universität Dresden150 enrolled

Overview

The purpose of this study is to examine the influence of selective laser trabeculoplasty (SLT) on ocular rigidity in glaucoma patients.

Ocular Rigidity (corneal hysteresis and corneal resistance factor) is measured with the Ocular Response Analyzer (Reichert) before and 4 weeks after SLT (Q-switched 532 nm frequency doubled neodymium yttrium aluminium garnet laser with a spot size of 400 µm and a 3-ns pulse duration). The trabecular meshwork is treated with 100 spots over 360° and an energy of 0,8 mJ. The purpose is to examine if selective laser trabeculoplasty changes ocular rigidity.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

150

Conditions

Glaucoma

Interventions

Selective Laser TrabeculoplastyPROCEDURE

100 spots with an energy of 0,8 mJ are applied over 360° of the trabecular meshwork of glaucoma patients with a Q-switched 532 nm frequency doubled neodymium YAG Laser.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: glaucoma patients (primary open angle glaucoma, ocular hypertension) over the age of 18 who need further IOP reduction to control their glaucoma Exclusion Criteria: other forms of glaucoma (angle closure, secondary glaucoma, congenital, juvenile), acute psychosis, epilepsy

Locations (1)

University Eye Clinic Dresden

Dresden, Saxony, Germany

Outcomes

Primary Outcomes

change in ocular rigidity

Is there a change in ocular rigidity (corneal hysteresis, corneal resistance factor) as measured with the Ocular Response Analyzer (Reichert) after selective laser trabeculoplasty?

Time frame: 4 weeks

Secondary Outcomes

IOP reduction

Is there an effective IOP drop after SLT?

Time frame: 4 weeks

Data from ClinicalTrials.gov

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