Does Administration of Etomidate and Propofol of the Anesthetic Induction of Elderly Hypertensive Patient Provide Superior Blood Pressure Stability in Response to Direct Laryngoscopy When Compared to Propofol or Etomidate Alone?

University of Mississippi Medical Center

Overview

This study will attempt to show that a combination of drugs, Etomidate and Propofol, provide a more stable blood pressure when used to put elderly hypertensive patients to sleep than either drug used alone.

Same as above.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

NONE

Conditions

Hypertension

Interventions

propofolDRUG

Propofol 1mg/kg will be given once to put the patient to sleep for surgery.

EtomidateDRUG

Etomidate 0.3mg/kg will be given once to put the patient to sleep for surgery.

Propofol and EtomidateDRUG

Etomidate 0.2mg/kg plus Propofol 0.5mg/kg will be given once to put the patient to sleep for surgery.

Eligibility

Sex: ALLMin age: 65 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients at least 65 years old, with a history of hypertension. Exclusion Criteria: * Patients less than 65 years old or without a history of hypertension.

Locations (1)

University of Mississippi Medical Center

Jackson, Mississippi, United States

Outcomes

Primary Outcomes

Blood pressure stability during anesthetic induction

Blood pressure will be measures every minute for 15 minutes following anesthetic induction

Time frame: 15 minutes

Data from ClinicalTrials.gov

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