"Volatile Anesthetic Protection Of Renal Transplants: VAPOR-1-trail

University Medical Center Groningen120 enrolled

Overview

To compare the renal protective properties of two currently used anaesthetic techniques - a sevoflurane-remifentanil/sufentanil combination with a propofol-remifentanil/sufentanil combination for anaesthesia in patients undergoing living donor kidney donation/transplantation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

120

Conditions

Kidney Donation/Transplantation

Interventions

procedure:sevoflurane-remifentanil/sufentanilDRUG

Active Comparator

volatile agent only during reperfusionDRUG

Active Comparator

propofol-remifentanil/sufentanilDRUG

Active Comparator

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients: Age \> 18 years Exclusion Criteria: * patient refusal * BMI\< 17, \>35 * neurological disorder * recent use of psycho-active medication, including alcohol. * Donor-recipient couples from the ABO-incompatible program * Altruistic donor

Locations (1)

University Medical Center Groningen

Groningen, Netherlands

Outcomes

Primary Outcomes

To compare the renal protective properties of two currently used anaesthetic techniques

Time frame: participants will be followed for the duration of hospital stay

Data from ClinicalTrials.gov

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