SNAP VS BIS(OAA/S) Scale During a Sedation Regimen With and Without Ketamine

Northwestern University25 enrolled

Overview

The study question: Does the SNAP-Index (SI) correlates better with the OASS than the BIS Monitor during sedation with ketamine? The study hypothesis: Since the SNAP II monitor seems to be more responsive during emergence of anesthesia, it will have a better correlation with the OASS than the BIS monitor with the use of ketamine.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

TRIPLE

Enrollment

Conditions

Pain

Interventions

Ketamine groupDRUG

ketamine bolus of 0.25mg/kg followed by an infusion set at 1.5 mcg /kg/min.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 64 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age : 18-64 years * ASA : I-III * Procedure : Breast or gynecological surgery * Anesthesia :Monitored anesthesia care Exclusion Criteria: * Pregnancy * Breast Feeding * Body Mass Index \>35kg/m2 * Drug or Alcohol abuse * Use anticonvulsants * History of CVA * Drop-out criteria: * Patient or surgeon request * Conversion to general anesthesia * Inability to obtain data from both monitors

Locations (1)

Northwestern Memorial Hospital

Chicago, Illinois, United States

Outcomes

Primary Outcomes

TcCO2 Above 50

% Time Tosca Monitor (TcCO2) above 50. A TcCo2 above 50 is indicative of hypoventilation.

Time frame: Intraoperative, an average of about 1 and 1/2 hours.

Data from ClinicalTrials.gov

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