Transcatheter aortic valve implantation (TAVI) is an alternative for patients, that are considered to be too sick for conventional aortic valve replacement. There is no conclusive opinion about the best anesthesiologic management of these patients. Sedation and general anaesthesia are both adequate and the current literature shows no benefit towards one of these methods. This study wants to investigate the influence of these two anesthesiologic managements on the cerebral oxygen saturation during the "rapid pacing"-period during valvuloplasty. The patients are randomised allocated to one of these two anaesthesiological managements. The investigators use the Near-Infrared Spectroscopy (NIRS) to measure the cerebral oxygen saturation. Parallel there will be a measurement of cerebral biomarkers to monitor cerebral hypoxia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
62
general anaesthesia is performed according to the hospitals standard
Sedation is performed according to the hospitals standard
Deutsches Herzzentrum München
Munich, Bavaria, Germany
Cerebral oxygen desaturation during the "rapid pacing" period and periprocedural
Biomarkers for cerebral ischemia will be measured up to 48 hours
Time frame: up to 48 hours
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.