Retinal Nerve Fibres Layers Thickness Study in Glaucomatous Patients

University of Roma La Sapienza

Overview

In this study the investigators are going to study the retinal nerve fibers layers (RNFL) modification of two groups of patients, one taking no drugs, the other taking forskolin, rutin and vitamins B1 and B2.

Study Type

INTERVENTIONAL

Conditions

Glaucoma

Interventions

forskolin, rutin and vitamins B1 and B2DRUG

Eligibility

Sex: ALLMin age: 30 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age (30-80 years); * Baseline Intraocular pressure (IOP) (20-32 mmHg): average untreated Intra Ocular Pressure (IOP) for both eyes as determined from 2 to 4 visits within a 6-months period; * Central Corneal Thickness (CCT) (475-650 µm): average of 3 different measurements from both eyes during the same visit; * Pattern standard deviation (PSD) (0,50-3,00 dB) average of both eyes as stated on the most recent visual field index report * Vertical Cup/Disk ratio (0,00-0,80): average of both eyes * All these data were entered into a calculator specially designed for STAR (Scoring Tool for assessing risk) II parameter. The patients were divided into low-, moderate- and high risk groups according to the result given by the calculator. Exclusion Criteria: -other ocular pathologies than glaucoma

Locations (1)

Univerisity La Sapienza

Latina, Italy

Outcomes

Primary Outcomes

retinal nerve fibres layer thickness

Secondary Outcomes

global risk threshold for glaucoma progression

Data from ClinicalTrials.gov

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