This study aims to study prospectively for 8 months a sample of bipolar patients with acute depressive episode in order to identify that factors associated with functional impairment, with especial attention to the presence of subsyndromal symptoms beyond the acute phase.
Study Type
OBSERVATIONAL
Enrollment
249
Research Site
Elche, Alicante, Spain
Research Site
Villajoyosa, Alicante, Spain
Difference between basal and final Functional Assessment Staging (FAST) score to evaluate the functional change
Time frame: Range of Days 0-3
FAST score to estimate the proportion of patients that not achieve functional remission
Time frame: Range of Days 0-3
Test Screen for Cognitive Impairment in Psychiatry (SCIP) to evaluate cognitive impairment both in the depressive phase and during clinical remission
Time frame: Range of Days 0-3
Mood chart (self-report)
Time frame: Range of Days 0-3
The presence of subsyndromal symptoms after the acute depressive phase using Montgomery-Asberg Depression Rating Scale (MADRS), Young Mania Rating Scale (YMRS), Diagnostic and Statistical Manual of Mental disorders (DSM-IV-TR)
Time frame: Range of Days 0-3
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Research Site
Almería, Almería, Spain
Research Site
Barcelona, Barcelona, Spain
Research Site
Granollers, Barcelona, Spain
Research Site
San Boit de LLobregat, Barcelona, Spain
Research Site
Córdoba, Cordoba, Spain
Research Site
Granada, Granada, Spain
Research Site
Lleida, Lerida, Spain
Research Site
Monforte de Lemos, Lugo, Spain
...and 14 more locations