Atopic dermatitis is a recurrent pruritic skin disorder which has a significant morbidity and impaired quality of life due specially pruritus and physical visible skin lesions. The propose of this trial is evaluate the effectiveness of clemastine fumarate 1, 0 mg/g + dexamethasone 0, 5 mg/g compared to dexchlorpheniramine maleate 10 mg/g in eczema treatment.
Study design: • Double blinded, superiority, prospective parallel-group, intend to treat trial. Study design: * Experiment duration: 22 days * 2 visits (days 1,7,15 and 22) * Reducing Eczema Area and severity index evaluation * Adverse events evaluation
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
310
Medcin instituto da Pele
Osasco, São Paulo, Brazil
Reduction / improvement of signs and symptoms
The reduction of signs an symptoms will be evaluated by OSAAD index.
Time frame: DAY 22
Adverse Events Evaluation
Adverse events will be collected and followed in order to evaluate safety and tolerability.
Time frame: DAY 22
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.