The Impact of Probiotic Bacteria on the Efficacy of Anti-retroviral Therapy and Recurrence of Bacterial Vaginosis

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's150 enrolled

Overview

Purpose of the proposed research is to determine the impact of probiotic yogurt supplemented with Lactobacillus rhamnosus (Fiti) compared to regular yogurt on the well-being of women living with HIV.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

150

Conditions

Bacterial Vaginosis

Interventions

Yogurt supplemented with L. rhamnosus fitiDIETARY_SUPPLEMENT

200 ml of L. rhamnosus fiti at 10\*9 cfu/ml daily for 30 days.

Yogurt not supplemented with a probiotic strain.DIETARY_SUPPLEMENT

200 ml yoghurt without L. rhamnosus fiti daily for 30 days.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion criteria: * Confirmed HIV infection; * Being treated with anti-retroviral medication for \> 6 months. Exclusion criteria: * Pregnancy; * Hypersensitive to fermented milk; * Intolerant for lactose; * Complaints of bacterial vaginosis requiring treatment

Locations (1)

Sekou-Toure Regional Hospital

Mwanza, Tanzania

Outcomes

Primary Outcomes

Vaginal microbiota of HIV patients.

Time frame: 30 days

Secondary Outcomes

Bacterial vaginosis.

Time frame: 30 days

Data from ClinicalTrials.gov

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