This clinical study is designed to evaluate the efficacy and safety of silodosin in a 12 week treatment of patients with severe urinary disorders associated with benign prostatic hyperplasia (BPH).
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
100
Silodosin will be administered during 12 weeks, 8 mg (4 mg x 2 cap) QD with morning meal.
Seoul national university hospital
Seoul, South Korea
Total International prostate symptom score(IPSS) score before and after treatment
Assess the improvement of lower urinary tract symptoms with change in total IPSS score before and after treatment.
Time frame: For 12 weeks
Quality of life(QoL) score before and after treatment
Assess the improvement of lower urinary tract symptoms with change in QoL score before and after treatment.
Time frame: For 12 weeks
Maximal urinary flow rate(Qmax) before and after treatment
Assess the improvement of lower urinary tract symptoms with change in Qmax before and after treatment.
Time frame: For 12 weeks
Voiding score of IPSS before and after treatment
Assess the improvement of lower urinary tract symptoms with change in voiding scores before and after treatment.
Time frame: For 12 weeks
Storage scores of IPSS before and after treatment
Assess the improvement of lower urinary tract symptoms with change in storage scores before and after treatment.
Time frame: For 12 weeks
Post void residual urine volume(PVR) before and after treatment
Assess the improvement of lower urinary tract symptoms with change in post void residual urine volume(PRV) before and after treatment.
Time frame: For 12 weeks
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