The purpose of this study is to evaluate the impact of Bedside Paediatric Early Warning System (Bedside-PEWS) on early identification of children at risk for near and actual cardiopulmonary arrest, hospital mortality, processes of care and PICU resource utilization.
The Bedside Paediatric Early Warning System (Bedside PEWS) is a scientifically developed documentation-based system of care designed to identify children who are clinically deteriorating while admitted to hospital inpatient wards. It was developed and validated by the applicants. The investigators have preliminary data demonstrating that the Bedside PEWS addresses multiple factors (communication, hierarchy, secondary review) contributing to delayed treatment of children at risk. In our pilot study of implementation at a single site the investigators showed statistically significant reductions in late transfers, 'stat' calls, decreased apprehension when nurses called physicians to review patients, and improved communication. Our preliminary data show that the Bedside PEWS score is superior to other methods being used to identify children at risk for impending cardiopulmonary arrest. A 2-year cluster-randomized trial will evaluate the impact of Bedside PEWS on clinical outcomes, processes of care and resource utilization in 22 paediatric hospitals.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
144,539
The Bedside Paediatric Early Warning System (Bedside PEWS) is a documentation-based system of care that will replace existing documentation systems for vital signs in inpatient ward areas in hospitals randomized to implement Bedside-PEWS. Frontline staff education within each hospital will occur over a period of three months preceding a 5 week run-in implementation phase, which will be followed by hospital-wide implementation. The Bedside-PEWS documentation record will become the primary method of documentation for vital signs and related data.
Hospitals randomized to standard care will continue with established methods of care. This will include the use of calling criteria and/or the expert model to identify children at risk. As in intervention hospitals, existing MET-RRT practices, established staffing and documentation practices will continue.
HUDERF: Queen Fabiola Children's University Hospital
Brussels, Belgium
Alberta Children's Hospital
All Cause Hospital Mortality (Intervention Phase)
All cause hospital mortality includes all deaths of eligible inpatients who were cared for in an eligible inpatient ward and will be prospectively assessed for 52 weeks following the 5-week run in period at intervention hospitals. The following sub-group analyses will be performed: \[1\] Hospital size. Hospitals with \>200 eligible inpatient ward beds will be one group and those with \<200 eligible inpatient ward beds the other. \[2\] Hospitals with and without medical emergency teams. \[3\] Hospitals with ECMO for children. \[4\] patients with urgent PICU admission initiated in an inpatient ward.
Time frame: for 52 weeks starting at Week 31
Number of Significant Clinical Deterioration Events
This will be defined as the provision of significant respiratory or circulatory therapies or cardiopulmonary resuscitation in the 12 hours before transfer from inpatient ward, or death without DNR order in an inpatient ward. The following sub-group analyses will be performed: \[1\] Hospital size. Hospitals with \>200 eligible inpatient ward beds will be one group and those with \<200 eligible inpatient ward beds the other. \[2\] Hospitals with and without medical emergency teams. \[3\] Hospitals with ECMO for children. \[4\] patients with urgent PICU admission initiated in an inpatient ward.
Time frame: for 26 weeks starting at Week 0 (baseline) and for 52 weeks starting at week 31 (intervention)
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Calgary, Alberta, Canada
Stollery Children's Hospital
Edmonton, Alberta, Canada
Victoria General Hospital
Victoria, British Columbia, Canada
Saint John Regional Hospital
Saint John, New Brunswick, Canada
IWK Health Centre
Halifax, Nova Scotia, Canada
McMaster Children's Hospital
Hamilton, Ontario, Canada
London Health Sciences Center University Hospital
London, Ontario, Canada
The Hospital for Sick Children
Toronto, Ontario, Canada
Centre hospitalier universitaire Sainte-Justine
Montreal, Quebec, Canada
...and 12 more locations