Real-Time MV/kV Image Guided Radiation Therapy

Stanford University

Overview

In current radiation therapy, imaging (typically, cone beam CT imaging or two orthogonal X-ray projection imaging) is done for patient setup before radiation dose delivery. Dose delivery typically takes 2 to 5 minutes depending on the delivery technique used for treatment. A tumor target may change its position during the dose delivery process. The goal of this project is develop a real-time imaging strategy to monitor the tumor position during dose delivery and evaluate its potential clinical impact.

Study Type

OBSERVATIONAL

Conditions

Prostate Cancer

Interventions

Real-time kV/MV Prostate ImagingDEVICE

The kV images will be acquired using onboard kV X-Ray imaging system existing in the clinical linear accelerator (LINAC).

Eligibility

Sex: MALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * The study population will be drawn from available patient population that will be treated using IMRT/VMAT. The Stanford population of IMRT/VMAT will be taken as roughly representative of prospective IMRT patients and will not be subdivided by any additional characteristics. Exclusion Criteria: * The study population will be drawn from available patient population that will be treated using IMRT/VMAT. The Stanford population of IMRT/VMAT will be taken as roughly representative of prospective IMRT patients and will not be subdivided by any additional characteristics.

Outcomes

Primary Outcomes

To verify improved tumor targeting accuracy using IMRT (intensity modulated radiation therapy) and VMAT (volumetric modulated radiation therapy)

Time frame: 2 years

Data from ClinicalTrials.gov

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