Fractional CO2 Laser Assisted Photodynamic Therapy

Inclusion Criteria: * Age 18 or older * Skin type I-III * Fertile women using secure birth control * Moderate to severe actinic keratoses in the face or on the hands, * Difficult to treat nodular basal cell carcinomas in the face Exclusion Criteria: * Pregnancy or breast feeding patients * Patients with porphyria * Patients with Gorlins syndrome * Patients with a tendency to produce hypertrophic scars or keloids * Patients with known allergy to Metvix * Patients who are not considered able to follow the treatment protocol (e.g. severely alcoholic, dementia, mentally ill etc.) * Patients with pigmented or morphea basal cell carcinomas * Know herpes simplex virus infection in treatment areas