Drug-Disease Interaction in Crohn's Disease

Inclusion Criteria: * Willingness to adhere the study protocol * Males of females of non-childbearing potential aged from 18 to 65 years * Lab values no more than 10% outside of the lab's stated normal range unless the subject is in the Crohn's disease group and the values are related to the disease, or if the PI decides the abnormality is not clinically significant * The subject is healthy (except for the Crohn's disease group) * Non-smoker for at least 3 months Exclusion Criteria: * History of hypersensitivity to verapamil * Significant history of gastrointestinal (other than Crohn's disease), liver, kidney, or any other disease or condition known to interfere with the absorption, distribution, metabolism or excretion of drugs * Significant history of allergies * Significant history of cardiovascular or hematological disease * Significant history of asthma, chronic bronchitis or bronchospastic conditions * Presence of diabetes mellitus or any other condition which would preclude fasting * Maintenance therapy with any drug (except those prescribed for Crohn's disease) or a history of drug dependence, alcohol abuse, or serious psychological disease * Any clinically significant illness other than Crohn's disease in the previous 30 days prior to the study * Use of enzyme-modifying drugs in the previous 30 days before the study * Blood donation in the previous 56 days or multiple blood samplings in the previous 30 days before the study * History of fainting upon blood sampling * Participation in another clinical trial within 30 days of the study * Narcotic use * Glucocorticoid treatment in the last 30 days